Table 4.
Variance in Allele Length of the Tn Microsatellite for the World, Non-Africans, and Africans, by Haplotype[Note]
World |
Non-Africans |
Africans |
|||||||
Haplotype | N | S2 | -lnP | n | S2 | -lnP | n | S2 | -lnP |
B001 | 401 | .010 | .010 | 366 | .011 | .011 | 34 | .0 | .0 |
B002 | 292 | .284 | .159 | 222 | .005 | .004 | 69 | .955 | .938 |
B003 | 128 | .038 | .040 | 116 | .009 | .009 | 12 | .242 | .410 |
B004 | 104 | .0 | .0 | 102 | .0 | .0 | 2 | .0 | .0 |
B005a | 59 | .103 | .107 | 48 | .106 | .110 | 11 | .091 | .095 |
B006b | 91 | .154 | .207 | 87 | .152 | .203 | 1 | .0 | .0 |
B019 | 5 | 1.200 | .511 | 3 | .0 | .0 | 2 | .0 | .0 |
B051 | 2 | .500 | NA | 2 | .500 | NA | … | … | … |
B007 | 35 | .281 | .06 | … | … | … | 35 | .281 | .59 |
B010 | 12 | 1.091 | .69 | … | … | … | 12 | 1.091 | .693 |
B012 | 9 | 2.250 | .401 | … | … | … | 9 | 2.250 | .401 |
B046 | 5 | .200 | .223 | … | … | … | 5 | .200 | .223 |
b061 | 5 | .200 | .223 | … | … | … | 5 | .200 | .223 |
Note.— Only haplotypes showing variable Tn are shown. In calculating the proportion of intact ancestral alleles, P, the major allele was assumed to be ancestral, which is a fragile assumption when made with a low number of chromosomes. The -lnP values were nevertheless calculated, for comparison with S2. NA = not applicable.
Three B005 chromosomes with Tn allele 15 were not considered in the calculation. We assumed that this length allele was acquired in B005 by recombination rather than by mutation (see text).
Because of the likely origin of three B006 haplotypes in African Americans by admixture (see text), only B006 found in the Rimaibe was retained in the African sample.