Figure 3.

Morphometric analysis of lesion area in the aortic tree. Aortae were stained en face with Sudan IV, and lesion area was measured as a percentage of total aortic area. (A) Lesion area in male and female mice. *P ≤ 0.05; significantly different from Apoe^–/– control mice. (B) Representative photographs of the en face aortae from female Apoe^–/–, Cd36^–/–Apoe^–/–, and Msr1^–/–Apoe^–/– mice. The boxed region indicates the area of reduced lesions observed in the Cd36^–/–Apoe^–/– female mice.