Table 5.
Comparison of the Multipoint HLOD Scores Obtained in the First Data Set and in the Expanded Data Set
|
HLOD Score in |
||||
| Locus | Marker | Marker Positiona(cM) | First DataSet (n=56) | Expanded DataSet (n=102) |
| GD-2 | D20S195 | 47.8 | 3.5 | 3.3b |
| GD-3 | DXS8020 | 101.2 | 2.5 | −.5 |
| HT-1 | D13S173 | 103.6 | 2.1 | −.9 |
| HT-2 | D12S346 | 102.0 | 2.3 | 3.4 |
| 7q | D7S502 | 81.2 | 1.4 | 2.3 |
| 8q | D8S284 | 136.4 | 1.8 | 3.5 |
| 10q | D10S537 | 93.3 | 1.8 | 4.1 |
a
The distance of the marker from the p-terminal end of the chromosome.
b
This multipoint LOD score was obtained for the white non-Italian families (n=73) without assuming heterogeneity.