Figure 3.

A, Identification of potential premutation allele in the general population. The consensus between haplotype B and a possible premutation allele in an unaffected control is depicted. Identical coloring indicates the regions where the haplotypes are shared. The sequence of the DM2 expansion region in the possible premutation allele is indicated below the haplotype. B, The schematic diagram showing the repeat configurations of the DM2 expansion region on 24 normal control alleles, 3 expanded affected alleles, and the putative premutation allele.