TABLE 3.
Secreted factors implicated in the intestinal inflammatory response in IBD
Class | Factor |
---|---|
Cytokines | IL-12, TNF, IFN-γ, IL-10, IL-18, IL-15, lymphotoxins alpha and beta, IL-1β |
Chemokines | IL-8, MCP-1, ENA-78, RANTES |
Growth factors | Keratinocyte growth factor, vascular endothelial growth factor, epidermal growth factors, trefoil factors |
Other | Matrix metalloproteinases |