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HLA class II associations with IBD
| HLA definition
|
Association with disease
|
||
|---|---|---|---|
| Serologic specificity | DNA genotypes | UC | CP |
| DR103 | DRB1*0103 | Positive | |
| DR2a | DRB1*1501–DRB1*1504 | Positive to DR2 overall | Negative association with DR2 |
| DRB1*1601–DRB1*1606 | Positive to DR15, negative to DR16; positive to DRB1*1501, DRB1*1502 | ||
| DR7 | DRB1*0701 | Positive | |
| DR9 | DRB1*0901 | Positive | |
| DR52c | DRB3*0301 | Positive | |
Serologic subtype DR2 can be subtyped as DR15 or DR16.
