Table 1.

Summary of AGRE Families^[Note]

			No. in Families with
	Total No. of		Two AffectedSiblings		Three AffectedSiblings		Four AffectedSiblings
PhenotypeDefinition	Families	Probands	Families	Probands	Families	Probands	Families	Probands
Narrow	285	716	265	530	17	51	3	12
Broad	345	833	307	614	34	102	4	16

Note.— Data summarize structure of families in the narrowly and broadly defined phenotype groups (as described in “Families and Methods” section).