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. 2025 Feb 6;66(2):18. doi: 10.1167/iovs.66.2.18

Table 3.

Prevalence of Single Bilateral VFI Stratified by Age, Gender, and Ethnicity in the PIONEER Study

Gender Ethnicity
All (N = 2380) Male (N = 1089) Female (N = 1291) Chinese (N = 1198) Malay (N = 603) Indian (N = 579)
N Weighted, % (95% CI) N Weighted, % (95% CI) n Weighted, % (95% CI) n Weighted, % (95% CI) n Weighted, % (95% CI) n Weighted, % (95% CI)
Bilateral VAI
 60–69 100 10.5% (8.2, 13.1) 40 9.2 (6.2, 13.0) 60 11.7 (8.3, 15.7) 45 10.4 (7.7, 13.7) 29 10.4 (7.1, 14.7) 26 11.0 (7.3, 15.6)
 70–79 140 17.5 (14.4, 20.8) 51 14.1 (9.9, 19.1) 89 20.4 (16.1, 25.2) 74 17.3 (13.8, 21.2) 37 20.4 (14.8, 27.1) 29 15.9 (10.9, 22.2)
 ≥80 192 30.9 (26.1, 36.0) 74 25.9 (20.0, 32.5) 118 34.0 (27.1, 41.3) 103 30.8 (25.4, 36.7) 51 36.4 (27.6, 45.9) 38 23.7 (17.2, 31.3)
 P trend <0.001 <0.001 <0.001 <0.001 <0.001 0.002
 Total 432 15.3 (13.6, 17.2) 165 12.5 (10.2, 15.1) 267 17.8 (15.3, 20.6) 222 15.4 (13.4, 17.6) 117 15.6 (12.8, 18.7) 93 13.8 (11.0, 17.0)
Bilateral CSI
 60–69 143 11.5 (9.3, 14.1) 63 12.0 (8.7, 16.0) 80 11.1 (8.1, 14.7) 41 9.5 (6.9, 12.6) 69 24.3 (19.4, 29.7) 33 14.4 (10.1, 19.6)
 70–79 225 26.4 (22.9, 30.2) 80 21.3 (16.3, 27.0) 145 30.9 (25.9, 36.3) 109 25.4 (21.4, 29.8) 65 35.8 (28.8, 43.2) 51 27.5 (21.2, 34.6)
 ≥80 303 46.5 (41.3, 51.7) 114 35.5 (29.1, 42.4) 189 53.4 (45.9, 60.7) 146 45.3 (39.4, 51.3) 89 64.2 (55.0, 72.7) 68 40.7 (32.9, 48.9)
 P trend <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
 Total 671 20.7 (18.9, 22.6) 257 17.3 (14.7, 20.2) 414 23.7 (21.2, 26.4) 296 19.4 (17.3, 21.6) 223 31.2 (27.5, 35.2) 152 20.9 (17.6, 24.6)
Bilateral CVI
 60–69 60 6.1 (4.4, 8.3) 36 8.2 (5.4, 11.9) 24 4.0 (2.2, 6.7) 26 6.0 (4.0, 8.6) 16 5.9 (3.4, 9.4) 18 7.9 (4.7, 12.2)
 70–79 72 8.2 (6.1, 10.7) 37 8.9 (5.7, 13.2) 35 7.5 (4.9, 11.0) 33 7.8 (5.4, 10.8) 15 8.1 (4.6, 13.0) 24 13.5 (8.8, 19.5)
 ≥80 125 16.2 (12.5, 20.4) 53 17.0 (12.1, 22.9) 72 15.7 (10.7, 21.8) 49 15.1 (11.0, 19.9) 27 19.4 (12.7, 27.8) 49 29.5 (22.4, 37.4)
P trend <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
 Total 257 8.1 (6.8, 9.6) 126 9.4 (7.3, 11.9) 131 6.9 (5.4, 8.8) 108 7.8 (6.3, 9.6) 58 7.8 (5.8, 10.4) 91 11.9 (9.3, 14.9)
DPI
 60–69 167 15.1 (12.5, 18.0) 96 19.3 (15.2, 24.1) 71 11.0 (7.9, 14.8) 59 13.6 (10.5, 17.2) 63 22.8 (17.9, 28.2) 45 20.0 (15.0, 25.8)
 70–79 255 30.6 (26.8, 34.6) 123 32.3 (26.5, 38.6) 132 29.1 (24.2, 34.4) 125 29.6 (25.3, 34.3) 72 39.1 (31.9, 46.5) 58 32.3 (25.5, 39.7)
 ≥80 299 43.1 (38.0, 48.4) 149 46.0 (39.1, 53.1) 150 41.3 (34.2, 48.7) 147 41.8 (36.0, 47.8) 77 55.6 (46.1, 64.7) 75 46.5 (38.6, 54.4)
P trend <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
 Total 721 23.5 (21.5, 25.6) 368 26.1 (22.9, 29.4) 353 21.2 (18.7, 23.9) 331 22.5 (20.1, 24.9) 212 30.2 (26.4, 34.2) 178 26.3 (22.6, 30.4)

Weighted prevalences were calculated with sampling weights specific to each age group, gender and ethnicity to adjust for oversampling and post-stratification weights to align to the population distribution based on the 2020 Singapore Census. P trend will not be computed for counts less than 5 in any age group or if the total count is less than 20.