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. 2025 Feb 6;66(2):18. doi: 10.1167/iovs.66.2.18

Table 4.

Prevalence of Multiple Bilateral VFI Stratified by Age, Gender and Ethnicity in the PIONEER Study

Gender Ethnicity
All (N = 2380) Male (N = 1089) Female (N = 1291) Chinese (N = 1198) Malay (N = 603) Indian (N = 579)
N Weighted, % (95% CI) n Weighted, % (95% CI) n Weighted, % (95% CI) n Weighted, % (95% CI) n Weighted, % (95% CI) n Weighted, % (95% CI)
Any 2 Bilateral VFI
 60–69 74 5.8 (4.2, 7.7) 36 6.8 (4.4, 10.1) 38 4.8 (2.9, 7.3) 20 4.6 (2.8, 7.0) 36 12.8 (9.1, 17.3) 18 7.9 (4.7, 12.2)
 70–79 132 16.8 (13.8, 20.2) 60 16.1 (11.7, 21.3) 72 17.5 (13.4, 22.2) 72 16.9 (13.5, 20.8) 32 17.1 (12.0, 23.2) 28 15.2 (10.3, 21.3)
 ≥80 142 18.5 (14.8, 22.7) 67 20.4 (15.2, 26.5) 75 17.3 (12.4, 23.2) 60 17.0 (12.9, 21.8) 41 30.8 (22.6, 40.2) 41 24.8 (18.2, 32.4)
 P trend <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
 Total 348 10.8 (9.4, 12.3) 163 11.0 (8.9, 13.4) 185 10.5 (8.7, 12.6) 152 10.1 (8.5, 11.9) 109 15.7 (12.8, 19.0) 87 11.8 (9.2, 14.8)
Any 3 Bilateral VFI
 60–69 15 1.3 (0.6, 2.5) 8 1.5 (0.5, 3.5) 7 1.1 (0.3, 2.8) 5 1.2 (0.4, 2.7) 7 2.5 (1.0, 5.1) 3 1.3 (0.3, 3.9)
 70–79 47 5.2 (3.6, 7.3) 12 3.0 (1.2, 5.9) 35 7.1 (4.6, 10.4) 21 4.8 (3.0, 7.3) 15 8.4 (4.8, 13.4) 11 5.9 (3.0, 10.3)
 ≥80 94 13.2 (10.0, 16.9) 37 11.5 (7.5, 16.6) 57 14.2 (9.8, 19.7) 47 12.9 (9.3, 17.2) 25 16.6 (10.6, 24.2) 22 12.9 (8.1, 19.2)
P trend <0.001 <0.001 <0.001 <0.001 <0.001
 Total 156 4.1 (3.3, 5.0) 57 3.1 (2.1, 4.4) 99 5.0 (3.8, 6.4) 73 3.9 (3.0, 5.1) 47 5.4 (3.8, 7.4) 36 3.9 (2.6, 5.6)
All 4 Bilateral VFI
 60–69 11 1.0 (0.4, 2.1) 6 1.4 (0.4, 3.4) 5 0.6 (0.1, 2.0) 4 0.9 (0.3, 2.3) 3 1.1 (0.2, 3.3) 4 1.7 (0.5, 4.3)
 70–79 10 0.6 (0.2, 1.3) 7 1.0 (0.2, 2.6) 3 0.2 (0.0, 0.7) 1 0.3 (0.0, 1.4) 4 2.2 (0.6, 5.5) 5 2.9 (1.0, 6.7)
 ≥80 36 6.5 (3.9, 9.9) 12 4.4 (2.0, 8.3) 24 7.7 (4.0, 13.1) 17 6.3 (3.5, 10.4) 12 8.8 (4.3, 15.7) 7 5.0 (2.0, 10.2)
P trend <0.001 0.021
 Total 57 1.6 (1.1, 2.3) 25 1.6 (0.8, 2.8) 32 1.6 (0.9, 2.7) 22 1.5 (0.9, 2.4) 19 2.2 (1.2, 3.6) 16 2.4 (1.3, 4.1)

Weighted prevalences were calculated with sampling weights specific to each age group, gender and ethnicity to adjust for oversampling and post-stratification weights to align to the population distribution based on the 2020 Singapore Census. P trend will not be computed for counts less than 5 in any age group or if the total count is less than 20.