Table 5.
Median Estimates of f and 95% CIs over All Replicates, for Offspring of First Cousins, Using Marker Genotypes
Simulationa |
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Z1 | .065 (.019–.124) |
Z1′ | .070 (.022–.128) |
Z2 | .065 (.020–.127) |
Z2′ | .071 (.023–.132) |
Z3 | .066 (.000–.139) |
Z3′ | .076 (.012–.148) |
Marker allele frequencies are the theoretical ones (Z1, Z2, and Z3) or were estimated on a control sample of 30 individuals (Z1′, Z2′, and Z3′). Each simulation included 1,000 replicates. Z1 = SNPs every 1.67 cM, frequency .2/.8; Z2 = microsatellites every 5 cM, frequency .02/.08/.3/.3/.3; Z3 = microsatellites every 10 cM, frequency .02/.08/.3/.3/.3.