Figure  1.

MAPH probe locations on 8p23.1. Positions of the MAPH probes (A–N) used to screen 8p23.1 for copy number variation are shown by arrows, together with the ORRs named “REPP” and “REPD” by Giglio et al. (2001). The area identified as involved in the copy number variation is shown in detail and is represented twice in this genome assembly (November 2002 assembly; for details, see the University of California–Santa Cruz [UCSC] Genome Bioinformatics Web site). The probe marked with an asterisk (*) showed increased dosage in 8p23.1 EVs but maps to ORR sequences and was not included in the main MAPH probe set. RefSeq = reference sequence.