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The data are represented as means±S.E.M. *P<0.05 compared with the saline-treated wild-type mice.
| Genotype | Treatment | Plasma ACTH (pg/ml) | Plasma corticosterone (pg/ml) |
|---|---|---|---|
| Wild-type | Saline (n=6) | 121±20 | 179±38 |
| Mepyramine (n=6) | 77±9* | 89±26* | |
| Apoe−/− | Saline (n=8) | 57±5 | 206±30 |
| Mepyramine (n=9) | 62±11 | 224±10 |
