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. 2005 Jul 18;102(30):10634–10639. doi: 10.1073/pnas.0500147102

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Copyright © 2005, The National Academy of Sciences

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Fig. 3. — Effect of ischemia reperfusion injury. After 25 days reperfusion, the fraction of lost cardiac myocytes (a) appears larger in JAM-A^-/- mice (^*, P < 0.05 vs. JAM-A^+/+) when compared with the respective sham-operated mice (JAM-A^-/-, n = 10; JAM-A^+/+, n = 6); n.d., not detectable. (b) Compensatory hypertrophy of cardiac myocytes surviving ischemia-reperfusion was significantly higher in JAM-A^-/- than in JAM-A^+/+ (^*, P < 0.05 vs. JAM-A^+/+;§, P < 0.05 vs. JAM-A^-/- sham; #, P < 0.05 vs. JAM-A^+/+ sham mice). Data are means ± SEM. Data were analyzed by using Student's t test.