Table 3. Transmission disequilibrium test and genotype frequency of TLR5 stop codon in SLE clinical subgroups.

SLE characteristic		T/NT for 1174C	T, %	P value	1174CC, n	1174CT; n (%)	P value
Renal	+	9:2	81.8	0.035	72	4 (5.3)	0.76
	–	8:4	66.7	0.25	96	7 (6.8)
Arthritis	+	13:5	72.2	0.059	147	11 (7.0)	0.61
	–	4:1	80.0	0.17	19	0 (0)
Hematologic	+	10:5	66.7	0.20	83	8 (8.8)	0.22
	–	6:1	85.7	0.047	77	3 (3.8)
α-CL Ab	+	8:2	80.0	0.058	54	4 (6.9)	1.00
	–	6:3	66.7	0.31	66	6 (8.3)
α-dsDNA Ab	+	9:6	60.0	0.44	97	9 (8.5)	0.21
	–	8:0	100.0	0.00087	61	2 (3.2)
α-Sm Ab	+	2:2	50.0	1	19	2 (9.5)	0.67
	–	14:4	77.8	0.019	110	9 (7.6)

Transmission (T) rates and genotype frequency of TLR5 SNP C1174T were evaluated in 199 SLE patients with different available clinical features. Rates indicate transmission of 1174C (wild-type allele). For the genotype frequency analysis, only SLE patients who had the indicated clinical data available were included. α-CL, anticardiolipin; Sm, Smith antigen.