Fig. 5.

Functional connectivity of the hypothalamus. Gray arrows show significant relationships (P < 0.05) in frogs that heard irrelevant acoustic stimuli (P. enesefae whine and chuck-only), and black arrows indicate relationships in frogs exposed to behaviorally relevant stimuli (conspecific whine and whine-chuck). (A) egr-1 levels in midbrain and thalamic nuclei implicated in auditory processing are significant predictors of hypothalamic expression patterns. Relationships between auditory and hypothalamic regions do not vary with relevance of stimulus. (B) egr-1 correlations between hypothalamic regions differ based on behavioral relevance of acoustic stimulus.