Table 1. Linear associations between hypothalamic and auditory regions do not depend on behavioral relevance of stimulus.

	Auditory-hypothalamic regression			Behavioral relevance included
Hypothalamic region	Adjusted R2	F	P	R2 change	F change	P
Dorsal hypothalamus	0.295	2.313	0.082	0.015	0.214	0.810
Lateral hypothalamus	0.558	4.969	0.004	0.128	1.105	0.428
Periventricular nucleus	0.386	1.348	0.296	0.032	0.353	0.709
Preoptic area	0.088	1.289	0.324	0.055	0.598	0.565
Posterior tuberculum	0.539	4.765	0.006	0.099	1.266	0.341
Suprachiasmatic nucleus	0.809	13.728	0.000	0.043	0.920	0.510
Ventral hypothalamus	−0.176	0.530	0.799	0.136	1.329	0.298

The auditory-hypothalamic regression column summarizes relationships between egr-1 levels in all seven auditory regions (independent predictor variables) and each hypothalamic region (dependent variable). The behavioral relevance column shows little improvement in auditory-hypothalamic multiple regressions when variables encoding behavioral relevance of stimulus and interaction terms are added. (see Statistics in Materials and Methods).