Table 2.

Radioiodide uptake in wild-type and transfected ARO cells

Cell type	Iodide uptake (cpm/well)
		P	+ KClO4	P
ARO wild-type	133 ± 35		78 ± 26	**0.09
ARO pCMV	137 ± 42	*0.9	82 ± 47	**0.2
ARO-PAX8 clone 8	307 ± 43	*0.006	126 ± 27	**0.003
ARO-PAX8 clone 21	257 ± 36	*0.01	104 ± 26	**0.004
FRTL-5	4350 ± 320
CHO	40 ± 12

Iodide uptake was analyzed as described in Methods. The FRTL-5 cells and CHO cells were used as positive and negative controls, respectively. Iodide uptake was expressed as the mean ± SD of values obtained from three separate experiments. Statistic analysis was performed using the one-factor ANOVA, followed by t test. P < 0.05 was considered statistically significant.

* ARO PAX8 clone 8, clone 21 and ARO pCMV vs ARO wild-type;

** Uptake with vs Uptake without KClO₄