Table 1.
Substance P release evoked by activation of transient receptor potential ankyrin 1.
| GPR35+/+ | GPR35−/− | ||||||
|---|---|---|---|---|---|---|---|
| Unstim | ASP7663 | ASP7663+ AM0902 |
ASP7663+ CS |
Unstim | ASP7663 | ASP7663+ CS |
|
| Mean SP (pg/mg) | 0.274 | 2.403 | 0.277 | 0.113 | 0.335 | 1.65 | 3.92 |
| SEM (pg/mg) | 0.102 | 1.038 | 0.076 | 0.038 | 0.097 | 1.15 | 1.47 |
Data show mean SP detected (pg SP/mg tissue) using a chemiluminescent immunoassay (analysis shown in Fig. 8B).
SP, Substance P.