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. 2025 Feb 10;20:11. doi: 10.1186/s13722-024-00531-0

Table 3.

Estimated marginal means (SDs), and effect sizes for symptom change at minimal dose (Session 3) and final session (Session 5)

Measure Session 1 Session 3 Session 5 Cohen’s d (Session 1 to 3) Cohen’s d (Session 1 to 5)
PCL-5 48.9 (15.7) 41.0 (18.5) 39.8 (19.6) 0.46 0.51
PHQ-9 15.3 (6.34) 12.5 (6.14) 12.7 (5.9) 0.46 0.43

 PCL-5: PTSD Checklist, DSM-5 version; PHQ-9: patient health questionnaire, 9-item version; SDs: standard deviations. Estimated marginal means (EMMs) were used to adjust for missing data and within-subject correlations in the repeated measures design, as recommended by a reviewer. EMMs provide a model-based estimate of the average effect at each session, accounting for the overall statistical model