Table 1.
SPM-Producing Cell Types of the Lung
| Cell Type | SPM | Reference |
|---|---|---|
| Alveolar macrophages | RvD1 and LXA4 | Townsend et al. (160) |
| M2-like macrophages | Resolvins, protectins, maresins | Werz et al. (59) |
| Mast cells | RvD1 | Puzzovio et al. (161) |
| PMN-platelets | MaR1 | Abdulnour et al. (121) |
| PMN-airway epithelial cells | Lipoxins, RvD1 | Cox et al. (162) Isopi et al. (32) |
| Apoptotic PMN | RvDs, MaR1, LX | Dalli and Serhan (68) |
| Human monocytes Toll-like receptor 7 agonist (COVID-19 patients) | PD1, RvD5 | Koltsida et al. (163) Navarini et al. (164) |
| Eosinophils | LXA4, PDx, RvD2 | Miyata et al. (165) Serhan et al. (166) |
| Microparticles | 17-HDHA, 14-HDHA | Dalli and Serhan (68) |
DHA, docosahexaenoic acid
LX, lipoxin
Ma, maresin
PD1, protectin D1
Rv, resolvin
SPM, specialized pro-resolving mediators