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. 2025 Jan 28;6:1520067. doi: 10.3389/froh.2025.1520067

Table 1.

Table of included studies.

Study Year Vitamin deficiency Key findings Therapeutic implications
Tabel et al. 2020 B12, Folate Increased ulcer frequency; mucosal sensitivity Importance of vitamin testing
Padayatty et al. 2021 C Delayed healing; gingival bleeding Supplementation recommended
Hugar et al. 2017 Folate Severe RAS linked to folate deficiency Folate therapy for severe cases
Freitas et al. 2019 B12, C, Folate Reduction in ulcer frequency with supplementation Multivitamin approach