Table 1.
Table of included studies.
| Study | Year | Vitamin deficiency | Key findings | Therapeutic implications |
|---|---|---|---|---|
| Tabel et al. | 2020 | B12, Folate | Increased ulcer frequency; mucosal sensitivity | Importance of vitamin testing |
| Padayatty et al. | 2021 | C | Delayed healing; gingival bleeding | Supplementation recommended |
| Hugar et al. | 2017 | Folate | Severe RAS linked to folate deficiency | Folate therapy for severe cases |
| Freitas et al. | 2019 | B12, C, Folate | Reduction in ulcer frequency with supplementation | Multivitamin approach |