Table 1:
Subject demographics and clinical characteristics stratified by the development of asthma during the outcome period.
| Asthma | |||
|---|---|---|---|
| No (n=89,245) | Yes (n=836) | p-value | |
| Minimum age, years | 50.6 (36.5; 62.4) | 42.2 (30.4; 53.3) | <0.001 |
| Gender, female | 53,866 (60.4) | 633 (75.7) | <0.001 |
| Race | <0.001 | ||
| Black | 9,060 (10.2) | 121 (14.5) | |
| White | 77,026 (86.3) | 688 (82.3) | |
| Other | 3,159 (3.5) | 27 (3.2) | |
| Height, cm | 168.2 (162.6; 177.8) | 166.5 (160.0; 174.0) | <0.001 |
| Weight, kg | |||
| Weight t0, kg | 80.3 (66.7; 95.7) | 79.8 (66.7; 95.3) | 0.948 |
| Weight t1, kg | 80.7 (67.1; 95.8) | 80.7 (67.6; 95.7) | 0.607 |
| Weight t2, kg | 81.1 (67.6; 96.2) | 81.0 (67.6; 97.5) | 0.528 |
| Weight t3, kg | 81.2 (67.7; 96.6) | 81.7 (68.7; 98.3) | 0.193 |
| Weight change t3-t0, kg | 0.9 (−2.8; 4.8) | 1.5 (−2.0; 5.5) | <0.001 |
| Record length*, years | 7.5 (5.2; 10.7) | 8.1 (4.1; 10.2) | <0.001 |
| Years to outcome | ---- | 5.7 (4.0; 8.7) | |
| History of tobacco use, yes | 14,495 (16.2) | 63 (7.5) | <0.001 |
| Metabolic dysregulation components | |||
| Diabetes mellitus | <0.001 | ||
| Free | 74,159 (83.1) | 744 (89) | |
| Chronic | 4,792 (5.4) | 30 (3.6) | |
| Developed | 10,294 (11.5) | 62 (7.4) | |
| Hypertension | <0.001 | ||
| Free | 45,854 (51.4) | 508 (60.8) | |
| Chronic | 12,420 (13.9) | 102 (12.2) | |
| Developed | 30,971 (34.7) | 226 (27) | |
| High-density lipoprotein† | 0.398 | ||
| Free | 74,899 (83.9) | 695 (83.1) | |
| Chronic | 2,489 (2.8) | 32 (3.8) | |
| Developed | 11,857 (13.3) | 109 (13.1) | |
| Triglycerides‡ | 0.872 | ||
| Free | 76,224 (85.4) | 709 (84.8) | |
| Chronic | 2,400 (2.7) | 24 (2.9) | |
| Developed | 10,621 (11.9) | 103 (12.3) | |
Data are presented as the median (lower; upper quartile) or number (%)
*
Median patient record length from t3 to last International Classifiers of Disease Billing code date.
†
< 50 mg/dL in males and < 50 mg/dL in females
‡
> 150 mg/dL