TABLE 1.
Days p.i. | Virus titer (mean log10 EID50 ± SD/g)
|
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Nasal turbinates | Lungs | Brain | Liver | Spleen | Kidneys | Heart | Pancreas | Colon | Bursa of Fabricius | |
1 | 5.2 ± 1.9 | 5.7 ± 2.5 | 5.0, 5.5 | 5.0 ± 2.1 | 5.9 ± 2.3 | 5.0 ± 2.2 | 4.3 ± 2.2 | 6.0, 6.3 | 6.3, 6.8 | 6.6, 6.1 |
Two-week-old specific-pathogen-free chickens were infected intranasally and orally with 50 μl of virus (a total of 105 PFU). Three chickens were sacrificed on day 1 p.i., and viral titers were determined in embryonated chicken eggs. When virus was not recovered from all three chickens, individual titers were recorded. By day 2, the remaining chickens had died.