TABLE 3.
Virus titers in organs of mice infected with HK213Egg or HK213CK virusa
| Virus and days p.i. | Virus titer (mean log10 EID50 ± SD/g)
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Nasal turbinates | Lungs | Spleen | Kidneys | Heart | Brain | Pancreas | Colon | |
| HK213Egg | ||||||||
| 1 | 2.2 ± 0.04 | 6.3 ± 0.2 | —b | 1.7 | — | — | 2.0 | — |
| 3 | 3.9 ± 0.5 | 7.8 ± 0.4 | 2.6, 3.5 | 1.9 ± 0.5 | — | — | 2.6 ± 0.6 | 2.6, 3.1 |
| 6 | 4.4 ± 1.0 | 7.6 ± 0.4 | 1.6, 1.6 | — | 1.7 | 1.9, 2.1 | — | — |
| HK213CK | ||||||||
| 1 | — | 4.3 ± 0.02 | — | — | — | — | — | — |
| 3 | 1.6, 2.5 | 6.8 ± 0.4 | — | — | — | — | 1.5 | 2.8 |
| 6 | — | 6.5 ± 0.3 | — | — | — | — | 2.0 | — |
a
BALB/c mice, anesthetized with isoflurane, were inoculated intranasally with virus (7 × 102 PFU/50 μl). Three animals from each infected group were euthanized on day 1, 3, or 6 p.i. for virus titration. When virus was not recovered from all three mice, individual titers were recorded.
b
—, Virus was not isolated.