FIG. 5.

Model of C3 protein interactions. TYLCV C3 consists of 134 amino acids containing three hydrophobic clusters shown as filled boxes above the rectangular diagram. pRBR interaction with C3 was decreased by mutations clustered in the first 13 and final 9 amino acids of C3 (shown as solid regions). C3 homo-oligomerization was adversely affected by mutations in the middle of the protein, shown shaded within the rectangular region. PCNA interaction with C3 (dashed line) was impacted by mutations near the beginning of C3 to amino acid 95. C1 interaction with C3 (dotted line) was sensitive to mutations between amino acids 28 and 128.