Table 2.

Results from linear mixed model analyses

Dependent variable	Estimate	SE	CI (95%)	t	p
BDI-II a c
Time	–1.60	0.23	–2.04 to − 1.15	–7.1	< 0.001
Time x treatment	–0.12	0.32	–0.76 to 0.53	–0.4	0.720
HDRS a d
Time	–6.93	0.97	–8.86 to − 5.01	–7.2	< 0.001
Time x treatment	–1.50	1.39	–4.25 to 1.26	–1.1	0.283
GAF-S b d
Time	9.61	1.37	6.89 to 12.32	7.0	< 0.001
Time x treatment	0.82	1.96	–3.09 to 4.73	0.4	0.677
GAF-F b d
Time	11.63	1.38	8.90 to 14.37	8.5	< 0.001
Time x treatment	0.15	1.98	–3.79 to 4.09	0.1	0.938
WSAS b c
Time	–1.38	0.20	–1.78 to − 0.98	–6.9	< 0.001
Time x treatment	0.38	0.29	–0.19 to 0.94	1.3	0.192
SF-12 (MCS) b d
Time	8.56	1.95	4.71 to 12.41	4.4	< 0.001
Time x treatment	–0.48	2.78	–5.96 to 5.00	–0.2	0.863
SF-12 (PCS) b d
Time	–0.58	1.43	–3.43 to 2.27	–0.4	0.689
Time x treatment	0.02	2.05	–4.04 to 4.09	0.0	0.991
GAD-7 b c
Time	–0.50	0.11	–0.72 to − 0.28	–4.5	< 0.001
Time x treatment	–0.11	0.16	–0.43 to 0.20	–0.7	0.481

^a Primary outcome. ^b Secondary Outcome. ^c Time points 0, 2, 4 and 7 months. ^d Time points 0 and 7 months. HDRS = Hamilton Depression Rating Scale; BDI-II = Beck Depression Inventory II; GAF-S = Global Assessment of Functioning, Symptom Score; GAF-F = Global Assessment of Functioning, Functioning Score; WSAS = Work and Social Adjustment Scale; SF-12 (MCS) = Short Form Health Survey, Mental Health Component Scale; SF-12 (PCS) = Short Form Health Survey, Physical Component Scale; GAD-7 = Generalized Anxiety Disorder-7