Table 1.
unit | length | gene location | pep | name | mean | sd |
GCA | 23 | cds | LQQQQQQQQQQQQQQQQQQQQQQQ | AR | 20.36 | 4.11 |
CAG | 15 | cds | QQQQQQQQQQQQQQQH | DRPLA | 12.44 | 3.9 |
GGC | 17 | cds | GGGGGGGGGGGGGGGGGE | AR | 15.1 | 3.54 |
CAG | 19 | cds | QQQQQQQQQQQQQQQQQQQQ | TBP | 17.1 | 3.01 |
ACC | 13 | cds | LPPPPPPPPPPPPP | NULL | 11.5 | 2.12 |
GGC | 8 | cds | GGGGGGGGG | GDF7 | 9 | 1.73 |
CTG | 6 | cds | GSSSSSR | PCDH12 | 7.2 | 1.55 |
CCG | 9 | cds | PAAAAAAAAA | NULL | 6 | 1.41 |
GGGGCC | 4 | cds | APAPAPAPAP | CDKN1C | 3.33 | 1.15 |
GGC | 6 | cds | GGGGGG | NULL | 6.67 | 1.03 |
The ten most unstable coding repeats organized by descending standard deviation. Repeats highlighted in bold are known disease-associated repeats. (Note: trailing non-consensus amino acids are not artefactual output. Repeat units continue to be detected at the DNA level even it they do not completely achieve the consensus. For example in the second row above, the corresponding DNA sequence (CAG)15 CA contains a trailing CA (of the subsequent CAT codon) that translates into histidine).