Table 1.

Distribution of clinically and genetically relevant variables in a cohort of women at baseline of the observational period 1993 – 2003. The total number of women in this analysis is 4320, i.e. excluding 17 women with a final diagnosis of a possible/potential VTE. Deviations from this number are due to missing information

Variables
Continuous variables		n	Mean (SD)
Age (years)		4320	26.0 (8.6)
Life births, number		1910	1.7 (0.8)
BMI§		4309	23.3 (4.1)
Protein C (% of normal)		4315	102.4 (15.8)
AT (% of normal)		4316	98.4 (11.3)
Categorical parameters			Percent (%)
Own history of VTE	No	4279	99.0
	Yes	41	1.0
Family history	No	3840	88.9
	Yes	480	11.1
Age, alternative	<30	2843	65.8
	≥ 30	1477	34.2
Family history of varicous veins	No	2395	55.4
	Yes	1925	44.6
Family history of MI	No	3830	88.7
	Yes	490	11.3
BMI, alternative	<25	3218	74.7
	≥ 25	1091	25.3
Ever use of hormone replacement	No	4031	93.7
	Yes	270	6.3
Family history of stroke	No	4013	92.9
	Yes	307	7.1
Ever use of oral contraceptives	No	346	8.0
	Yes	3973	92.0
Education level: Abitur&	No	3119	73.2
	Yes	1139	26.8
Ever smoker	No	2022	46.8
	Yes	2296	53.2
Laboratory & genetic markers
Factor V Leiden mutation1	No	4035	93.7
	Yes	271	6.3
Prothrombin mutation1	No	4088	96.6
	Yes	142	3.4
MTHFR1	No	1798	42.5
	Yes	2432	57.5
Protein C deficiency#	No	4117	95.4
	Yes	198	4.6
AT deficiency#	No	4106	95.1
	Yes	210	4.9

¹ Homozygote & heterozygote together

^§

Body mass index (kg/m²)

^&maturity for university

^# definition see methods