Table 1.

Suggestive and Significant LODs (and P Values) for 71 and 102 Multiplex White Families with Vitiligo^[Note]

		LOD (P) in
Chromosomeand Distance	Marker(s)	71 Familiesa	102 Families
1:
12.2 cM	D1S214	2.17 (.000335)	NS
73.7 cMb	D1S2797-D1S2890	5.56 (.000000282 )	5.59 (.000000279 )
7:
89.4 cMc	D7S669	2.87 (.000131)	3.73 (.0000208)
8:
54.2 cMd	D8S505	1.95 (.00135)	3.36 (.0000418)
9:
88.1 cM	D9S167-D9S283	NS	2.34 (.000238)
11:
4.1 cM	D11S4046-D11S1338	1.93 (.00142)	NS
13:
109.4 cM	D13S173	NS	2.30 (.000563)
17:
4.3 cMe	D17S849-D17S831	NS	3.07 (.0000852)
19:
34.9 cM	D19S221-D19S226	2.45 (.000388)	2.62 (.000254)
107.8 cM	D19S210	2.31 (.000551)	NS
22:
7.7 cM	D22S420-D22S539	2.30 (.000561)	2.98 (.000106)

Note.— Only linkage signals achieving significant (LOD⩾3.3 and/or P⩽.000049 [shown in boldface italics]) or suggestive (LOD⩾1.86 and/or P⩽.0017) de novo linkage thresholds (Terwilliger and Ott 1994; Lander and Kruglyak 1995; Nyholt 2000) are reported; the significant linkage threshold for independent replication (i.e., SLEV1) is P⩽.01 (Lander and Kruglyak 1995). NS denotes not suggestive. Genome positions have been updated using the deCODE genome map (Kong et al. 2002) and sequence-based STS map (National Center for Biotechnology Information). All gene symbols have been approved by the HUGO gene nomenclature committee.

^aFain et al. 2003.

^bAIS1.

^cAIS2.

^dAIS3.

^eSLEV1.