Table 2.
Comparisons of A/S Ratios among European, Asian, and African Sequence Sets
|
No. of Substitutions(A, S)a |
No. of Substitutions(A, S)a |
No. of Substitutions(A, S)a |
|||||||
| Gene | AFR | EUR | Pb for AFR vs. EUR | AFR | ASIA | Pb for AFR vs. ASIA | ASIA | EUR | Pb for ASIA vs. EUR |
| ND1 | 4, 21 | 20, 34 | .040 | 4, 21 | 8, 10 | .083 | 8, 10 | 20, 34 | .589 |
| ND2 | 5, 24 | 23, 47 | .145 | 5, 24 | 3, 14 | 1.000 | 3, 14 | 23, 47 | .255 |
| CO1 | 7, 30 | 25, 64 | .370 | 7, 30 | 5, 18 | 1.000 | 5, 18 | 25, 64 | .608 |
| CO2 | 3, 11 | 8, 24 | 1.000 | 3, 11 | 8, 6 | .120 | 8, 6 | 8, 24 | .048 |
| AT8 | 2, 6 | 10, 11 | .408 | 2, 6 | 6, 2 | .132 | 6, 2 | 10, 11 | .238 |
| AT6 | 7, 14 | 32, 22 | .071 | 7, 14 | 12, 4 | .005 | 12, 4 | 32, 22 | .378 |
| CO3 | 4, 18 | 23, 30 | .063 | 4, 18 | 0, 12 | .273 | 0, 12 | 23, 30 | .005 |
| ND3 | 2, 6 | 5, 19 | 1.000 | 2, 6 | 1, 4 | 1.000 | 1, 4 | 5, 19 | 1.000 |
| ND4L | 0, 6 | 5, 9 | .260 | 0, 6 | 1, 2 | .333 | 1, 2 | 5, 9 | 1.000 |
| ND4 | 3, 31 | 19, 61 | .074 | 3, 31 | 10, 15 | .009 | 10, 15 | 19, 61 | .129 |
| ND5 | 8, 41 | 36, 95 | .172 | 8, 41 | 10, 16 | .047 | 10, 16 | 36, 95 | .345 |
| ND6 | 2, 15 | 13, 24 | .106 | 2, 15 | 7, 4 | .010 | 7, 4 | 13, 24 | .162 |
| CYb | 7, 33 | 31, 51 | .024 | 7, 33 | 12, 15 | .026 | 12, 15 | 31, 51 | .651 |
a
mtDNA sequences are stratified by continent of origin (AFR = Africa; EUR = Europe; ASIA = Asia/Native American). A = nonsynonymous substitutions; S = synonymous substitutions. Note that, in these analyses, haplogroup-associated and private substitutions are pooled into a single number.
b
P values were determined with Fisher’s exact test.