Table A.
No. with Genotype |
OR |
||||
Sample | WW | WM | MM | WM vs. WW | MM vs. WM |
AJ (Case-Control): | |||||
Cases | 23 | 10 | 3 | 1.69 | 4.67 |
Controlsa | 193.18 | 49.63 | 3.19 | … | … |
AJ+SOJ (Multiplex, TDT): | |||||
WM×WW | 12 | 18 | … | 1.5 | … |
WM×WM | 0 | 8 | 15 | ∞ | 3.75 |
MM×WM | … | 2 | 6 | … | 3.00 |
Combined | 1.83 | 3.50 | |||
Combined Mantel-Haenszel | 1.78 (95% CI 1.06–2.97) | 3.71 (95% CI 1.89–7.29) |
Note.— W = non-mutation-bearing haplotypes (A+G+H); M = all mutation-bearing haplotypes (B+C+D+E+F+I).
Values are Hardy-Weinberg expected frequencies; actual frequencies were 195 (WW), 46 (WM), and 5 (MM).