Table 4.
Multivariate analysis for baseline characteristics and treatment factors
| Factor | Level | No. | Progression-free survival | Local control | Regional control of neck | |||
|---|---|---|---|---|---|---|---|---|
| Adjusted HRa (95 % CIb) | Adjusted P value | Adjusted HR (95 % CI) | Adjusted P value | Adjusted HR (95 % CI) | Adjusted P value | |||
| ECOG-PSc | ≤1 | 24 | – | – | – | – | 1 | 0.069† |
| 2 | 9 | – | – | 4.883† (0.886, 50.977)† | ||||
| T classification | 2 or 3 | 16 | 1 | 0.273 | 1 | 0.096† | – | – |
| 4a | 17 | 3.646 (0.361, 36.82) | 7.321† (0.744, 980.123)† | – | ||||
| Intra-arterial infusion | Ipsilateral | 16 | 1 | 0.221 | – | – | 1 | 0.129† |
| Bilateral | 17 | 4.254 (0.418, 43.28) | – | 6.685† (0.636, 917.141)† | ||||
| Catheter infection | No | 29 | – | – | 1 | 0.061† | – | – |
| Yes | 4 | – | 6.030† (0.914, 39.897)† | – | ||||
* P < 0.05
† The hazard ratio, 95 % confidence interval, and P value were estimated using Cox regression with Firth’s penalized likelihood
aHazard Ratio; b 95 % confidence interval; c Eastern Cooperative Oncology Group performance status