Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Probability (Pr) of a type I error plotted against the number of SNPs (in chromosomal order) tested in the Keavney et al. (1998) data. The graph shows the expected increase in the false-positive rate for completely independent SNPs [i.e., 1-(1-α)M] (thick dashed line), by use of an Meff-Šidák correction [i.e., 1-(1-α)Meff] (thin dashed line), and from 50,000 permutations (thick solid line), for α=0.05.
