Table 1.

Mean and Variance of the Test Statistic (TS) for Each of the Four Analysis Methods, for Samples Consisting of 1,000 Phenotypes from Nuclear Families^[Note]

	Mean TS				Theoretical Mean TSc		Variance (TS)
Sibship Size,h2QTLa, and h2PGb	HE	VH	SR	VC	SR	VC	HE	VH	SR	VC
2:
.0:
.25	.50	.50	.50	.49	.50	.50	1.25	1.20	1.19	1.13
.50	.52	.53	.52	.53	.50	.50	1.38	1.42	1.37	1.43
.75	.52	.52	.52	.52	.50	.50	1.27	1.30	1.28	1.31
.2:
.05	2.51	3.52	3.51	3.29	3.62	3.63	7.96	11.79	11.49	9.30
.30	3.09	3.90	3.89	3.98	4.02	4.04	10.38	13.86	13.38	14.45
.55	4.18	4.85	4.82	4.98	4.86	4.90	14.31	17.17	16.61	18.19
.5:
.00	14.14	18.87	18.28	20.22	19.89	20.83	48.06	65.59	58.64	67.68
.25	19.37	23.30	22.33	26.77	25.13	27.00	63.92	80.93	69.66	100.72
4:
.0:
.25	.51	.51	.51	.49	.50	.50	1.29	1.36	1.36	1.23
.50	.51	.51	.51	.50	.50	.50	1.39	1.35	1.40	1.28
.75	.50	.50	.50	.48	.50	.50	1.27	1.25	1.24	1.14
.2:
.05	5.93	8.95	9.20	8.50	9.18	8.74	24.14	40.48	41.17	31.18
.30	7.70	10.16	11.10	10.50	11.07	10.49	32.04	46.97	51.90	43.38
.55	10.51	12.54	14.40	13.63	14.62	13.77	44.68	56.14	66.35	55.69
.5:
.00	40.44	55.29	58.52	57.90	63.93	58.76	174.70	274.89	272.00	235.11
.25	56.67	69.06	76.54	79.78	86.12	80.00	240.21	329.19	338.17	334.87
8:
.0:
.25	.52	.54	.54	.50	.50	.50	1.39	1.45	1.44	1.20
.50	.48	.50	.50	.47	.50	.50	1.25	1.46	1.39	1.13
.75	.49	.50	.52	.48	.50	.50	1.25	1.33	1.48	1.21
.2:
.05	12.76	19.93	21.38	17.77	21.01	17.93	64.78	125.32	131.78	75.00
.30	16.71	22.57	27.13	22.56	26.97	22.61	87.76	141.59	182.60	106.90
.55	23.41	28.25	37.01	30.39	37.49	30.66	131.50	181.16	261.05	145.45
.5:
.00	94.16	129.38	149.27	118.58	163.30	119.09	637.61	1165.91	1245.42	615.44
.25	131.64	160.88	200.71	164.20	229.06	164.59	923.16	1395.88	1660.64	903.14

Note.— The empirical mean and variance of the TS are based on 10,000 replicates.

^aProportion of the phenotypic variance due to QTL effects.

^bProportion of the phenotypic variance due to residual polygenic effects.

^cThe theoretical expected value of the test statistic was calculated as described by Sham et al. (2000a).