Table 4.

McDonald-Kreitman Tests^[Note]

	No. of Differences
Samplea	Silent	Replacement	Fisher’s Exact Test(P)
Africans (n=163):
Polymorphic	67	9
Fixed	45	0	.014
Non-Africans (n=73):
Polymorphic	36	9
Fixed	45	0	.002
Global (n=236):
Polymorphic	74	9
Fixed	45	0	.026

Note.— Nos. of SNPs and fixations found at silent and replacement sites are contrasted with a Fisher’s exact test (see the “Subjects and Methods” section).

^aSee table 1 for population samples. n = no. of chromosomes.