Table 2.
A. Data Simulated with Uniform Crossing Over and Uniform Conversion | |||||||
Rate |
|||||||
ρ | γ | a | g(γ)b | B(γ)c | a | g(ρ)b | B(ρ)c |
20 | 40 | 38.02 | .25 | .64 | 20.78 | .80 | .55 |
40 | 40 | 33.82 | .21 | .71 | 44.22 | .84 | .49 |
60 | 40 | 42.10 | .21 | .68 | 64.10 | .85 | .48 |
30 | 20 | 29.82 | .13 | .66 | 31.84 | .82 | .53 |
30 | 40 | 38.08 | .25 | .67 | 31.63 | .84 | .51 |
30 | 60 | 44.82 | .28 | .72 | 33.07 | .81 | .49 |
B. Data Simulated with Nonuniform Crossing Over and Uniform Conversion | |||||||
Rate |
|||||||
ρ | γ | a | g(γ)b | B(γ)c | a | g(ρ)b | B(ρ)c |
20 | 40 | 29.01 | .26 | .73 | 21.05 | .81 | .54 |
40 | 40 | 23.06 | .14 | .81 | 40.71 | .83 | .56 |
60 | 40 | 18.43 | .17 | .85 | 58.60 | .90 | .58 |
30 | 20 | 14.95 | .12 | .78 | 29.17 | .83 | .59 |
30 | 40 | 22.55 | .21 | .80 | 30.85 | .82 | .54 |
30 | 60 | 36.45 | .28 | .77 | 30.94 | .83 | .55 |
and denote the averages of the MLEs of gene-conversion () and crossing-over () rates for the 500 data sets simulated at the corresponding crossing-over (ρ) and gene-conversion (γ) rate.
g(γ) and g(ρ) denote the fraction of times and for a simulated data set is within a factor of 2 of the true γ and ρ, respectively (Wall 2000).
B(γ) and B(ρ)denote the fraction of times and are less than their true values.