Table 5.
Empirical Power of Testing a Set of Marker Combinations (α=0.05) for the Global Hypothesis
|
Empirical Power under Model |
|||||
| Recessive |
Dominant |
||||
| Data Structure,Maxmarker,and Window | No. of Combinations | Bonferronia | Global | Bonferronia | Global |
| Trios: | |||||
| 1: | |||||
| … | 5 | .409 | .441 | .230 | .250 |
| 2: | |||||
| Yes | 9 | .469 | .556 | .277 | .360 |
| No | 15 | .432 | .553 | .264 | .359 |
| 3: | |||||
| Yes | 12 | .526 | .601 | .436 | .524 |
| No | 25 | .439 | .580 | .339 | .479 |
| 5: | |||||
| Yes | 25 | .499 | .599 | .422 | .521 |
| No | 31 | .437 | .582 | .352 | .499 |
| Nuclear Families | |||||
| 1: | |||||
| … | 5 | .664 | .729 | .429 | .497 |
| 2: | |||||
| Yes | 9 | .753 | .819 | .556 | .640 |
| No | 15 | .743 | .823 | .559 | .666 |
| 3: | |||||
| Yes | 12 | .799 | .862 | .778 | .837 |
| No | 25 | .747 | .843 | .721 | .808 |
| 5: | |||||
| Yes | 25 | .779 | .854 | .773 | .840 |
| No | 31 | .728 | .835 | .714 | .810 |
a
The power of the procedure, which is based on Bonferroni-corrected smallest raw P value.