Table 2.
Normalized Bias for Allele-Specific TRD with Probability (s) |
||||
Frequency (p)and Pedigree | .6 | .7 | .8 | .9 |
.2: | ||||
A–F | .0071 | .091 | .19 | .34 |
B | .0097 | .015 | .047 | .070 |
C and D | .014 | .016 | .046 | .037 |
E | −.0023 | .014 | .050 | .093 |
F | .0059 | .084 | .17 | .30 |
.35: | ||||
A–F | .027 | .10 | .24 | .44 |
B | .0057 | .046 | .090 | .15 |
C and D | .017 | .014 | .058 | .087 |
E | .00075 | .037 | .052 | .11 |
F | .027 | .097 | .22 | .39 |
.5: | ||||
A–F | .033 | .11 | .24 | .42 |
B | .013 | .050 | .11 | .21 |
C and D | .011 | .022 | .065 | .11 |
E | .0036 | .026 | .061 | .084 |
F | .028 | .097 | .21 | .38 |
Note.— Normalized bias of Spairs (shown in bold italics) and Sad for alleles in frequency p that are preferentially transmitted by heterozygous individuals, with probability s. For Sad, pedigree A is unbiased.