Table 9.
Conditional Probabilityb for |
|||
ASP Maternal Allele Shared and a | Pedigree C | Pedigree D | Pedigree E |
None: | |||
0 | ΔfδF+Δmδf | Δmδm+ΔfδM | ΔfΔm |
1 | (1-Δf)δF+(1-Δm)δf | (1-Δm)δm+(1-Δf)δM | Δf(1-Δm)+Δm(1-Δf) |
2 | 0 | 0 | (1-Δf)(1-Δm) |
f: | |||
0 | Δm+(1-Δm)δF | Δm+(1-Δm)δM | Δm |
2 | (1-Δm)δf | (1-Δm)δm | 1-Δm |
F: | |||
0 | Δf+(1-Δf)δf | Δf+(1-Δf)δm | Δf |
2 | (1-Δf)δF | (1-Δf)δM | 1-Δf |
f=the grandpaternal allele; F=the grandmaternal allele.
Probability distributions for of pedigrees C, D, and E (fig. 1), conditional on the grandparental origin of the maternal allele shared by the ASP.