Figure 1.

Pedigrees of family with SCKL and western blot showing reduced ATR protein levels in affected patients. A and B, Pedigrees of the two Pakistani families with SCKL (SCKL1) included in this study. Identification numbers of the lymphoblast cell lines derived from these family members are noted below their respective symbols. C, Western blot of lymphoblast cell lines from these family members and two unrelated control lymphoblast lines (LB-5 and LB-12) probed with α-ATR. The blot was stripped and reprobed with α-tubulin to indicate relative protein-loading levels.