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. 2004 Aug 12;75(4):654–660. doi: 10.1086/422701

Figure 3.

Figure 3

Cells from patients with SCKL1 have increased fragile-site expression. A, Average total chromosome gaps and breaks. n=50 metaphases from each of two replicates for each condition. Fragile-site induction was achieved by addition of 0.4 μM aphidicolin 48 h before harvest. Error bars indicate the 95% CI. B and C, Frequency of FRA3B (B) and FRA16D (C) expression in cell lines from patients with SCKL1 and control individual; n⩾100 hybridizations from each of two replicates for each condition. Fragile-site induction was achieved by addition of 0.4 μM aphidicolin 48 h before harvest. Error bars indicate the SE.