Table 1.

Comparison of Linkage Statistics Analyses Using All 200 Families and Using Only the 147 Informative Families

	Result for
Statistic and Software	All 200 Families	147 Informative Families	Reference
Mean test Z value:
SIBPAL	14.07	17.56	Haseman and Elston 1972
MLS LOD score (2 df):
SPLINK	36.34	36.34	Holmans 1993
MLS LOD score (1 df):
GeneHunter	22.20	22.20	Kruglyak and Lander 1995
ASPEX sib_phase	22.20	22.20	Hinds and Risch 1996
NPL Sall Z score:
GeneHunter	6.70	7.82	Kruglyak et al. 1996
Allegro	7.82	7.82	Gudbjartsson et al. 2000
Merlin	7.82	7.82	Abecasis et al. 2002
GeneHunter-Plus Sall LOD score:
GeneHunter-Plus	22.20	22.20	Kong and Cox 1997
Allegro	22.20	22.20	Gudbjartsson et al. 2000
Merlin	22.20	22.20	Abecasis et al. 2002