Figure 2.

Long-range extended homozygosity for the core haplotype containing the persistence-associated alleles at LCT at various distances from LCT. The extent to which the common core haplotypes remains intact is shown for each chromosome in cM. The core region containing −13910C/T is shown as a black bar, and the LCT gene is oriented from left to right. Core haplotypes containing the persistence-associated allele (−13910T) are shown in red, and those containing the non-persistence–associated allele (−13910C) are shown in blue. Haplotypes are from European-derived U.S. pedigrees; all chromosomes with core haplotypes having a frequency ⩾5% in this population are depicted.