Table 1.

ADAMTS10 Mutations Identified in Three Families with WMS

Family	Countryof Origin	ParentsConsanguineous	Nucleotide Change	Amino Acid Change	MutatedExon(s)
1	Lebanon	Yes	709C→T/709C→T	R237X/R237X	6/6
2	Saudi Arabia	Yes	1190+1G→A/1190+1G→A	Frameshift causing a stop, 1 codon downstream	10/10
3	France	No	709C→T/810+1G→A	R237X/frameshift causing a stop, 20 codons downstream	6/6