Table 1.

Marker-Trait Association P Values in Selected Siblings from Sample 1 (112 Siblings, 42 Families)^[Note]

				P Value for Trait
Marker	LD Region	Minor AlleleFrequencya (%)	Risk Alleleb	OC-irreg	OC-choice	PD	READ	SPELL	PA
rs2817220	A	.23	Major	.0326		.0067			.0004
rs22252525	A	.13
rs807517	A	.24	Major			.0223			.0017
rs1054899	A	.34
rs2760184	A	.04
rs807527	A	.10
rs699463	A	.24	Major						.0068
rs807530	A	.41
rs807535	A	.10
rs807540	A	.08	Major	.0203			.0118	.0085
rs807545	A	.06	Major					.0244
rs807521	A	.06	Major					.0306
rs807525	A	.06	Major					.0308
rs807507	A	.43
rs807508	A	.06	Major					.0304
k_ex5	A	.30	Major						.044
rs4504469	B	.47	Major	.0003			.0231		.0005
rs4576240	B	.05
rs4472344	B	.03
rs4236032	B	.05
rs2745333	B	.45	Major	.0002			.0178		.0001
rs2179515	B	.40	Major	.0002			.0021
rs761101	B	.39	Major	.0002		.0255	.0003
rs6456624	B	.44	Major	.00006	.036	.0231	.0007
rs2328846	B	.41	Major	.00003			.0001		.0377
rs2235676	B	.14	Minor	.0008	.0442		.0029
rs2038137	B	.43	Major	.00006			.0002	.0285
k_pr_del	B	.41	Major	.00002			.0001		.0377
rs9467247	B	.19	Minor	.0002	.0167		.0005
rs1555090	B	.40	Major	.00003			.0001		.0377
rs2294689	B	.05
rs3033236	B	.17	Minor	.0066	.0288		.0046
rs3212232	B	.26
rs2143340	B	.17	Minor	.0012	.0128		.0011
rs2056998	B	.05
rs1061925	B	.11	Minor	.00006	.0213		.0003
th_ex1	B	.11	Minor	.0004	.0214		.0011
tt_th_del	B	.06
rs3181228	B	.15
rs2328847	C	.01
rs1555088	C	.34	Major	.0178
rs926529	C	.36	Major	.0177
rs1885211	C	.46	Major	.009
rs2092404	C	.34	Major	.0137			.0405
th_ex3	C	.04
rs3756814	C	.43	Minor	.0178
rs6456632	C	.15
rs2067573	C	.05

Note.— The selection included all the sibships with at least one sibling scoring <−0.5 SD on an average score of IQ-adjusted OC-irreg and PD. All reading-related measures are IQ-adjusted.

^aMinor allele frequency calculated in the founders only.

^bOnly alleles with nominally significant marker-trait association (P<.05) are shown.