Table 3.

Marker-Trait Association P Values in Two Independent Selected Samples^[Note]

		Selected Sibships from Samples 1 and 2, Combined (U.K.)(n = 313 Siblings [126 Families])							Selected Sibships from Sample 3 (U.S.)a(n = 290 Siblings [124 Families])
			P Value for Traitb							P Value for Traitc
Marker	LD Region	Risk Alleled	OC-irreg	OC-choice	PD	READ	SPELL	PA	Risk Alleled	PD	READ	SPELL	PA
rs699463	A	Major	.0032		.0231	.0279	.0153	.0112
rs4504469	B	Major	.0011		.0082	.004		.01
rs2179515	B	Major	.0012		.0131	.0004	.0232
rs761101	B	Major	.0025		.0057	.0006	.0325
rs6456624	B	Major	.0005		.0045	.0003	.0157
rs2328846	B	Major	.0007		.0017	.0003	.0155
rs2235676	B	Minor	.0023	.0009		.0041			Minor		.0131
rs2038137	B	Major	.0013		.0026	.0002	.0061
k_pr_dele	B	Major	.0011		.0032	.0002	.0086
rs9467247	B	Minor	.0006	.0003	.0373	.0003	.0016		Minor		.0038		.0421
rs1555090	B	Major	.001		.0029	.0003	.0131
rs3033236	B	Minor	.0134	.0104		.0073			Minor	.0421	.0023	.0145	.0204
rs2143340	B	Minor	.01	.0003		.0115			Minor		.0050	.0273	.0124
rs1061925	B	Minor	.0009	.0005		.0008			Minor		.0102	.0340
tt_th_dele	B								Minor				.0181
rs926529	C	Major			.0132
rs1885211	C
th_ex_3e	C
rs3756814	C	Minor	.0332
rs6456632	C	Major				.0415

Note.— All the reading-related measures were IQ-adjusted.

^aSingle-tailed P values for testing the same marker allele as in the U.K. samples.

^bIQ showed no significant association in this analysis.

^cOC-choice and IQ showed no significant association in this analysis.

^dOnly alleles that showed nominally significant marker-trait association (P<.05) are shown.

^ePolymorphisms identified by mutation screening analysis, which were not present in the public databases.