Table 4.
Association P Values of Most Common rs4504469, rs2038137, and rs2143340 Haplotypes with Reading-Related Measures[Note]
|
Selected Subset from Samples 1 and 2, Combined (U.K.) |
Selected Subset from Sample 3 (U.S.) |
||||||||||||
|
P Value for Traita |
P Value for Traitb |
||||||||||||
| Haplotype | Frequency (%) | OC-irreg | OC-choice | PD | READ | SPELL | Mean Effectc | Frequency (%) | PD | READ | SPELL | PA | Mean Effectc |
| 111 | .41 | .0306 | −.10 | .46 | −.01 | ||||||||
| 221 | .36 | .0019 | .0314 | .0017 | .0004 | .0165 | .24 | .31 | −.01 | ||||
| 112 | .12 | .0045 | .00007 | .0024 | .0246 | −.34 | .12 | .017 | .0367 | .0183 | −.23 | ||
| 211 | .05 | .03 | .05 | .0187 | .0119 | .0243 | .30 | ||||||
| 121 | .04 | −.04 | .04 | .0245 | .0413 | .33 | |||||||
| Others | .02 | −.10 | .02 | −.07 | |||||||||
Note.— All reading-related measures are IQ-adjusted. 1 = major allele; 2 = minor allele.
a
PA showed no significant association in this analysis.
b
OC-choice showed no significant association in this analysis.
c
Mean phenotypic effect relative to all other haplotypes, calculated across the different measures.