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. 2025 Jan 30;14:1473437. doi: 10.3389/fonc.2024.1473437

Table 3.

Univariate and multivariate analyses of clinicopathological parameters for OS.

Factor Univariate analysis Multivariate analysis
P HR (95%CL) P HR (95%CL)
Age
>60
≤60
0.034 1.245(1.015-1.526) 0.047 1.230(1.003-1.508)
LN Metastasis
>2
≤2
<0.001 1.474(1.186-1.843) 0.022 1.314(1.040-1.658)
Pathological stage
IIIa
IIb
<0.001 1.684(1.337-2.120) <0.001 1.629(1.272-2.088)
Gender
Male
Female
0.011 1.299(1.060-1.590) 0.137 1.170(0.951-1.439)
Surgical Method
Open
VATS
0.158 1.252(0.916-1.712)
Air dissemination
Yes
No
0.113 0.857(0.699-1.049)
Vascular invasion
Yes
No
0.935 0.992(0.810-1.214)
Chemotherapy
Yes
No
0.013 1.324(1.060-1.655) 0.613 1.065(0.835-1.357)
Targeted therapy
Yes
No
<0.001 0.565 (0.458-0.696) <0.001 0.531(0.430-0.655)
Radiotherapy
Yes
No
0.232 0.861(0.674-1.101)
Immunotherapy
Yes 0.303 1.161(0.874-1.543)
No

Bold means P < 0.001 was considered very significant.