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. 2025 Jan 30;14:1473437. doi: 10.3389/fonc.2024.1473437

Table 5.

Univariate and multivariate analyses of gene mutations.

Factor Univariate analysis Multivariate analysis
P HR (95%CL) P HR (95%CL)
VEGFA
+
-
0.673 1.091 (0.727-1.638)
TP53
+
-
<0.001 3.175 (1.972-5.102) <0.001 2.994 (1.852-4.831)
XPC
+
-
0.577 0.890 (0.592-1.339)
KDR
+
-
0.430 1.178 (0.785-1.767)
PIK3C2G
+
-
0.004 1.842 (1.220-2.778) 0.027 1.600 (1.055-2.427)
SLIT1
+
-
0.782 1.062 (0.696-1.618)
CCND1
+
-
0.289 0.815 (0.499-1.230)
CYP3A4
+
-
0.733 0.912 (0.539-1.543)
XPA
+
-
0.225 0.716 (0.418-1.227)

Bold means P < 0.001 was considered very significant.