TABLE 2.
Peptidea | Response (reference) | Amino acid sequenceb |
---|---|---|
Gag 221-245 | Th1 (13) | QGPIPMTARFIRGLGVPRERQMEPA |
Gag 250-269 | Th1 (13) | RQTYRQWIIEAMSEGIKVMI |
Pol 326-347 | Th1 (13) | LPQGFVLSPYIYQKTLQEILQP |
Pol 704-719c | Th (12) | EIVYFAWVPGHKGIYG |
Gag 13-32 | Th (12) and CTL (33) | KLEKVTVQGSQKLTTGNCNW |
Env 195-206PVd | CTL (33) | RVEDVMNTTEYW |
Pol 704-Env 195PV | Th (12) and CTL (33) | EIVYFAWVPGHKGIYGPGPGRVEDVMNTTEYW |
Ana-P16a | Unknown | LYLDTGIASFNFAYFGGELGVRFA |
Amino acid numbers for EIAV peptides are published elsewhere (53).
Minimal ELA-A1-restricted CTL epitope sequences are underlined. The artificial linker amino acid residues in the hybrid peptide Pol 704-Env 195PV are in boldface and italic.
The corresponding peptide in EIAVWSUS has a C at position 718; however, this peptide is recognized by horses infected with various strains including EIAVPV, EIAVWSUS, EIAVWY (12).